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Our Approach: Where Science Meets Efficacy and Safety

As women age, hormonal fluctuations are a natural part of the process, and many may experience various symptoms that can impact their well-being and quality of life. At Moment Health, we believe that every woman deserves access to quality solutions to navigate these hormonal changes safely and effectively. Our comprehensive approach combines scientific knowledge with cutting-edge research to provide evidence-based solutions tailored to individual needs.

1. Safe Ingredients.

Moment takes a revolutionary approach to hormone replacement therapy (HRT) by prioritizing the use of treatments with fewer additives. With a steadfast commitment to providing pristine formulations, Moment aims to redefine the standard for HRT practices.

Moment’s dedication to less additives means no peanut oil, color dyes, or titanium dioxide. As a pioneer in the field, Moment continues to inspire the medical community to embrace a future where patient health and product purity harmoniously coexist.

2. Effective solutions. 

At Moment, we take great care in selecting effective solutions that truly work. Our approach is rooted in rigorous scientific research and evidence-based practices. We meticulously evaluate and test each solution to ensure its efficacy and reliability in addressing specific health concerns.

At Moment, we take great care in selecting effective solutions that truly work. Our approach is rooted in rigorous scientific research and evidence-based practices. We meticulously evaluate and test each solution to ensure its efficacy and reliability in addressing specific health concerns.

PROGESTERONE

PROGESTERONE PRODUCTION DECLINES WITH AGE

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Progesterone usually declines with age, and yet is one of the most important hormones in the body.

As women age, their progesterone production diminishes. Supplementing natural bio-identical progesterone with a high quality cream or capsule may help fight stress, aging, chronic inflammation, estrogen excess, thyroid problems, infertility, and much more.

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ESTROGEN

  • Helps to regulate the menstrual cycle
  • Allows proliferative effect on tissue, which is why it’s needed for a baby to grow, but also why it is involved in cancer development
  • Responsible for breast development
  • Plays a role in vaginal dryness
  • Plays a role in fatigue
  • Plays a role in brain fog

Estrogen is made in both men and women. It’s needed to perform many roles in the body, but just like when oxalates are chronically or insulin is chronically high, problems can happen. The body like its balance.

  • Periods of estrogen dominance in a woman’s menstrual cycle are normal and needed for women to reproduce. Problems can arise when estrogen dominance is sustained.
  • Estrogen has messages (cell proliferation and growth) that make it important to have it opposed with sufficient progesterone.
  • Estrogen “regulates a plethora of biological processes, by affecting key pathways in cell proliferation, fate, survival & metabolism” (Fortini, 2019). It has also been known to promote cell proliferation through the activation of estrogen receptors.

Cell proliferation is the process by which a cell grows and divides to produce two daughter cells.

Estrogen has this action mostly via activation of growth factor pathways that prompt cells to divide. This mechanism is also needed for reproduction. However, this mechanism must be controlled so the message isn’t used for the wrong processes in the body.

It’s commonly said that “estrogen makes everything grow.” It helps grow a baby! It makes the lining of the uterus grow, promotes the growth of the egg, and keeps the vaginal tissue moist. Growth messages can be positive and negative-this is why estrogen must be balanced.

Keep in mind that while estrogen is needed for cell proliferation, it can also be a contraceptive and can mimic stress.

What matters is that estrogen is produced at normal levels and is balanced optimally to support you

TESTOSTERONE

Testosterone production usually declines with age in men and women.

  • Critical for many of your biological processes especially the building, maintenance and repair of your bones
  • Plays a role in libido
  • Plays a role in cardiovascular health.
  • Plays a role in immune system
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Testosterone can help with the immune system. This may be why men are known to recover from the flu faster than women. Testosterone may be protective against the flu (and this may be why men tend to recover from the flu quicker than women). These data suggest that androgen receptor signaling creates a local pulmonary environment that promotes downregulation of detrimental inflammatory immune responses to protect against prolonged influenza disease.

  • Healthy testosterone levels are associated with greater bone mineral density.
  • Healthy testosterone levels are associated with greater lean body mass. Total and free T were measured using sensitive assays in 232 community-dwelling women aged 67–94 years old. Free T was positively related to hip BMD, lean body mass, and body fat (all P < 0.05), with more than 10% differences in each outcome between women at the highest and lowest ends of the free T range, with attenuation after excluding estrogen users and adjusting for estradiol.

Testosterone is often thought of as just a “male hormone,” but it’s incredibly important for women too.

  • Testosterone helps to protect the heart. Older women with low blood testosterone and DHEA concentrations, but not low estrogen, were found to have twice the risk of a cardiovascular event such as a heart attack or heart failure than those with higher testosterone. The apparent protective effects of testosterone and DHEA appeared to emerge early, with the higher three quartiles for each hormone tracking together.
  • Healthy testosterone levels are associated with better mood. Thirty-four women completed the study and testosterone therapy resulted in statistically significant improvements in mood.

Conclusions: Testosterone therapy improves well-being, mood, and sexual function in premenopausal women with low libido and low testosterone.

DHEA

  • Decreases significantly with aging
  • Similar to progesterone
  • Plays a role in bone health
  • Plays a role in mental health
  • Highest-circulating steroid present in the human body
  • Helps produce other hormones, including testosterone and estrogen

DHEA is the highest-circulating steroid present in the human body and it helps to produce other hormones, including testosterone and estrogen. DHEA plays an important role in the brain, immune system, anti-aging, and overall health, but levels decrease by about 80% between ages 25 and 75.

As the levels of DHEA and DHEA-S decline with age, the brain loses its protective properties and becomes more sensitive to the ravages of neurological decline.

DHEA supplementation provides benefits for both early and late postmenopausal women. One study treated early (50-55 years and late postmenopausal women (60-65 years) with oral DHEA 50 mg/day for 6 months. Treatment with DHEA was associated with a progressive improvement of the menopausal symptoms(Gyencol Endocrin 2000).

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Sex steroid hormone levels and specifically high levels of estrogen and low levels of DHEA have been linked with depressive symptoms. One study showed “lowered dehydroepiandrosterone levels are an additional state abnormality in adult depression. Adrenal steroid changes are thus not limited to cortisol. 

Because dehydroepiandrosterone may antagonize some effects of cortisol and may have mood improving properties, these findings may have significant implications for the pathophysiology of depression” (Biol Psychiatry, 2000). Another study concluded, “In men and women, DHEAS levels and depressive symptoms were inversely associated” (Psychoneuroendocrinology, 2007). 

In addition, the National Institute of Mental Health studied 46 patients age 40-65 with major and minor depression. After six weeks of administering DHEA, 23 patients showed a 50% decrease in depressive symptoms. Ten patients chose to continue taking DHEA for one year at a low dose and remained free of depression.

CORTISOL​

  • Hormone released when organism is under stress
  • Equips our bodies for times of survival.
  • High levels linked to fatty liver
  • High levels linked to blood sugar dysregulation
  • Can be immunosuppressive

Cortisol impacts our sex hormones including estrogen, progesterone, and testosterone as well as insulin and thyroid. Cortisol should be highest upon waking and then lowest at nighttime. It is inversely related to melatonin levels.

When we are stressed, our brain activates our hypothalamus-pituitary-adrenal axis (HPA) and can down-regulate FSH and LH, which can cause lower progesterone levels and impact sleep and mood. The body’s shock response increases cortisol, decreases blood pressure, and increases water uptake from the blood by tissues and organs. As a result, arteries become constricted. This physiological response is a huge contributing factor to many negative symptoms. High cortisol can contribute to excess estrogen. Excess estrogen is stored in our fat cells and can result in insulin resistance.

Elevated cortisol can also suppress thyroid levels since it can create the inactive form of thyroid hormone and can cause symptoms of fatigue, weight gain, constipation, mood changes, hair loss, and decrease metabolism.

Common causes of high cortisol:
  • Emotional stressors and anxiety
  • Not eating enough
  • Diet low in protein
  • High estrogen
  • Overexercising
  • Low thyroid
4 Things To Know About Cortisol
  • Cortisol activates the aromatase enzyme (used for estrogen biosynthesis) and in the absence of progesterone, cortisol becomes more active, increasing aromatase activity.
  • Cortisol tends to rise with age.
  • High cortisol promotes. the development of fatty liver.
  • Patients with hair loss often have excess levels of cortisol.